Rebreathing estimate of CoHb 1960



Henderson M, Apthorp GH.  Rapid method for estimation of carbon monoxide in blood.  Brit Med J  1960: 2: 1853

“Each subject washed the nitrogen from his lungs by breathing 100% oxygen from a simple open circuit (Fig. 1) for a period of three minutes.  At the end of this time he was instructed to take a maximum inspiration and hold his breath.  The three-way tap (T) was then turned and exhaled through a carbon dioxide absorber, previously washed out with oxygen into an empty and rebreathed from this bag for a further three minutes.  The contents of the bag were then analysed for oxygen by the Haldane method and for carbon monoxide, using an infra-red meter.”

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